Proteomics and Small Molecule Mass Spectrometry Core


Affiliated School or College: School of Medicine

Core Facility Category
Biosciences

CWRU Proteomics and Small Molecule Mass Spectrometry Core in collaboration with the Case Center for Proteomics and Bioinformatics (CPB) was established in 2006. The core provides state-of-the-art proteomic instrumentation, computational resources and software for systems biology, proteomic methods development, small molecule mass spectrometry, consultation and training. The core is highly experienced in structural proteomics and quantification of proteins and small molecules by mass spectrometry. Core staff actively collaborate on grant proposals and the development of novel technologies that apply proteomics/mass spectrometry to biomedical research. The core provides liquid chromatography/mass spectrometry services for both large (proteins/peptides) and small (drugs, metabolites) molecules.

Organization Affiliations: Case Comprehensive Cancer Center

Customers: External and Internal

Hours

Monday-Friday

8 a.m.-4 p.m.

Location

School of Medicine, Department of Nutrition

Biomedical Research Building

Room 954

2109 Adelbert Ave

Cleveland, Ohio 44109

Rates

Preparatory Services

Services/Equipment

Academic

Industry

Protein Concentration Analysis (per sample) $41 $64
Sample Clean-up (per sample) $41 $64
C18 Processing (per sample) $41 $64
Digestion (per sample)
Includes reduction, alkylation and enzyme
$23 $38
Liquid Extraction (TSQ) $18 $28

Post-translational Modification

Services/Equipment

Academic

Industry

Global Phosphoproteome Analysis
Includes digestion, enrichment, LC/MS/MS and analysis
Contact for Quote Contact for Quote
Qualitative Phosphoproteomic Analysis (per sample)
Includes digestion, enrichment, LC/MS/MS and analysis
$608 $1,433
Post-translational Modifications (per sample)
Includes digestion, LC/MS/MS and analysis
$608 $1,433

Proteomic LC/MS/MS Analysis

Services/Equipment

Academic

Industry

Short Gradient (per sample) $232 $378
Medium Gradient (per sample) $325 $528
Long Gradient (per sample) $608 $988

Small Molecule LC/MS/MS Analysis

Services/Equipment Academic Industry
Short Gradient (per sample) $43 $69
Medium Gradient (per sample) $81 $127
Long Gradient (per sample) $157 $249

Small Molecule LC/MS/MS Set Up Fees

Services/Equipment Academic Industry
Short Gradient Set Up Fee (per study) $308 $486
Medium Gradient Set Up Fee (per study) $608 $967
Long Gradient Set Up Fee (per study) $915 $1,453

Quantitative Analysis

Services/Equipment Academic Industry
Expression Based Proteomics Contact for Quote Contact for Quote
iTRAQ Contact for Quote Contact for Quote
SRM (Selected Reaction Monitoring) Contact for Quote Contact for Quote

Other

Services/Equipment Academic Industry
Infusion $210 $341
Off-line HPLC $129 $201
ELISA Analysis $1,654 $2,620
Data Analysis $115 $185