Light Microscopy Imaging Core

colorful imagery viewed through microscope

Affiliated School or College: School of Medicine

Core Facility Category
Biosciences
Materials Characterization, Imaging & Spectroscopy

The Light Microscopy Imaging Core facilities (LMIC) at Case Âé¶¹Ó³»­ provide advanced imaging systems. including whole slide scanning, confocal microscopy, STED microscopy, lightsheet microscopy, and spatial omics. Supported by sophisticated data analysis software, these systems enable detailed studies of cells, tissues, and organisms, driving significant research discoveries. Join us in advancing scientific explorations!

Our instrument portfolio

Imaging-Based Spatial-Omic Platforms

  • Xenium — 10x Genomics
  • CosMx/AtoMx — Bruker Spatial Biology

LightSheet Microscopy

  • Cleared-Tissue LightSheet - 3i
  • Lattice LightSheet - 3i

Confocal Microscopy

  • HyVolution SP8 - Leica
  • TCS SP8 gated STED 3X - Leica
  • SPIN SR-10 Spinning Disc - Olympus

Whole Slide Scanner

  • NanoZoomer S60 (Brightfield and Fluorescent slides) — Hamamatsu Photonics

Widefield Microscopy

  • DM6000 Upright Microscope - Leica
  • DM6000 Inverted Microscope - Leica

Analysis Workstation and Remote Data Storage

  • Lambda Vector (2 GPUs for deep learning)
  • Analysis software
  • 250 TB of storage

Customers: External and Internal

Hours

9 a.m. to 5 p.m. on weekdays

Location

Case Âé¶¹Ó³»­

School of Medicine

Robbins Building E632

2210 Circle Drive

Cleveland OH 44106